After aquiring colo at .masterhost I’ve faced a need to choose software bundle to make it up & running. I hate to choose, so the process was quick: after looking around and discussing the matter with other geeks, I’ve made the following decision:

• Gentoo Linux
• Mail handling: QMail + vPopMail + ezmlm-idx + QMailAdmin + courier-imap
• Mail filtering: Qmail-Scanner, SpamAssassin, ClamAV
• Webmail: Horde IMP

All of the above is set up from Gentoo Portage with just a little intervention from system administrator and does the job very well: after all I have seamless virtual domain mail system that is fully manageable using web tools (except low-level operations like adding virtual domains, and except ezmlm-idx, because its web tools are ugly).